Professor Emeritus of Optometry and Vision Science
School of Optometry
Dean Emeritus Optometry 1992-2001
Introduction to the basis of common sight-reducing visual disorders with major public health implications for society (e.g., myopial cataract), diabetic and hypertensive eye disorders, developmental disorders (e.g., “lazy eye”), and environmentally induced diseases and disorders (solar eye burns, cataract); major approaches to the prevention, diagnosis and treatment of common disorders in terms of the biological and optical sciences underlying the treatment or prevention, including protection from, and action of, radiation on the eye (e.g., ultraviolet and microwave), common pharmacological actions on the eye, laser treatments, tissue damage and repair, allergic and immune responses, optical distortions and optical errors and their correction; review of the major developments in the prevention and treatment of eye disease and the impact of these treatments on society and health care delivery.
Introduction to psychophysical basis for clinical tests in acuity, perimetry, and color vision; the visual stimulus and photometry; visual receptors; psychophysical method and visual threshold; light sensitivity; contrast sensitivity; light and dark adaptation; temporal and spatial properties of visual function; color vision and abnormalities; changes with age and disease; visual illusion; basis for advanced diagnostic procedures.
Introduction for graduate students to sensory aspects of light and color vision, including psycho-physical methods, spectral response of the eye, mechanisms of sensitivity control, dark adaptation, color discrimination, mechanisms of normal and defective color vision.
Vision in diabetes; color vision; assessment of retinal function
Diabetes is the leading cause of severe vision loss in the working-age population (20-74 yrs). Diabetic retinopathy is responsible for the vast majority of this loss. Yet treatments of retinopathy by laser surgery, though dramatic, do not prevent, reverse or eliminate the retinopathy and are accompanied by significant vision side effects; laser treatments slow the progression of retinopathy and vision loss. Recent research efforts have been directed at direct pharmaceutical interventions to treat retinopathy.
New pharmacological candidates for treatment & prevention of diabetic retinopathy can only be evaluated if there are identifiable vision and functional risk factors identified PRIOR to the development of irreversible damage to the retina (retinopathy). Our research is directed toward identifying those vision and functional retinal markers.
We apply both human psychophysical (S-cone sensitivity) and electrophysiological (ERG & EOG) methods in our study of diabetics and non-diabetic controls.
Han Y, Bearse MA, Schneck ME, Barez S, Jacobsen C, Adams AJ. Towards optimal filtering of “standard” multifocal electroretinogram (mfERG) responses: Findings in normals and diabetic patients. B J Ophthalmol 88:4;543-540, 2004.
Bearse MA, Han Y, Schneck ME, Adams AJ. Retinal function in normal and diabetic eyes mapped with the slow flash multifocal electroretinogram. Investigative Ophthalmology and Visual Science, 45:296-304, 2004.
Han Y, Adams AJ, Bearse MA, Schneck ME. Multifocal electroretinogram (mfERG) and short wavelength automated perimetry (SWAP) measures in diabetic eyes with little or no retinopathy. Archives of Ophthalmology. In press February, 2004
Han Y, Bearse MA, Schneck ME, Barez S, et al. Multifocal electroretinogram (mfERG) delays identify sites of subsequent diabetic retinopathy. Investigative Ophthalmology and Visual Science, 45; 948-954, 2004
Schneck ME, Bearse MA, Han Y, Barez S, Jacobsen C, Adams AJ “Comparison of mfERG implicit time measures for detecting functional change in early diabetic eye disease” Documenta Ophthalmologica, submitted March 2004
Schneck ME, Fortune B, Adams AJ “Changes in the Human ERG in Response to Induced Variations in Blood Glucose” Documenta Ophthalmologica, submitted March 2004
Bearse MA, Han Y, Schneck ME, Barez S, Jacobsen C, Adams AJ “Local Multifocal Oscillatory Potential Abnormalities in Diabetes and Early Diabetic Retinopathy” Investigative Ophthalmology and Visual Science, submitted March 2004
Han Y, Schneck ME, Bearse MA, Barez S, Jacobsen C, Jewell NP, Adams AJ “Formulation and Evaluation of a Predictive Model to Identify the Sites of Future Diabetic Retinopathy” Investigative Ophthalmology and Visual Science, submitted April 8, 2004